What it does

MDMA releases serotonin, dopamine, and norepinephrine, producing warmth, empathy, and mild stimulation. Effects last 3–5 hours. Currently in FDA-track clinical trials for PTSD.

Safer-use principles

• —Test what you have. 'Molly' is one of the most-adulterated substances in the illicit supply — often contains cathinones, meth, or fentanyl.
• —Overheating and hyponatremia (drinking too much water) are the main risks at dance events. Rest every hour. Sip water — don't chug.
• —Space experiences by at least 6–12 weeks. Frequent use damages serotonin systems.
• —History of heart disease, uncontrolled hypertension, or serotonin-affecting medication (SSRIs, MAOIs) is a strong contraindication.

Dangerous combinations

MDMA + SSRIs or MAOIs risks serotonin syndrome. MDMA + stimulants adds cardiac and hyperthermia risk. MDMA + alcohol worsens dehydration.

If something goes wrong

High body temperature (>39°C), rigidity, confusion, seizures — call 911 and cool the person actively. Serotonin syndrome (fever, agitation, tremor, rigidity) is a medical emergency.